AOBPreview originally published online on April 17, 2009
Annals of Botany 2009 104(1):1-7; doi:10.1093/aob/mcp086
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BOTANICAL BRIEFING |
Sucrose-mediated translational control
1 Molecular Plant Physiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
2 Centre for BioSystems Genomics, POB 98, 6700 AB, Wageningen, The Netherlands
* For correspondence. Email s.j.hanson{at}uu.nl
Received: 24 November 2008 Returned for revision: 18 December 2008 Accepted: 5 March 2009 Published electronically: 17 April 2009
Background: Environmental factors greatly impact plant gene expression and concentrations of cellular metabolites such as sugars and amino acids. The changed metabolite concentrations affect the expression of many genes both transcriptionally and post-transcriptionally.
Recent Progress: Sucrose acts as a signalling molecule in the control of translation of the S1 class basic leucine zipper transcription factor (bZIP) genes. In these genes the main bZIP open reading frames (ORFs) are preceded by upstream open reading frames (uORFs). The presence of uORFs generally inhibits translation of the following ORF but can also be instrumental in specific translational control. bZIP11, a member of the S1 class bZIP genes, harbours four uORFs of which uORF2 is required for translational control in response to sucrose concentrations. This uORF encodes the Sucrose Control peptide (SC-peptide), which is evolutionarily conserved among all S1 class bZIP genes in different plant species. Arabidopsis thaliana bZIP11 and related bZIP genes seem to be important regulators of metabolism. These proteins are targets of the Snf1-related protein kinase 1 (SnRK1) KIN10 and KIN11, which are responsive to energy deprivation as well as to various stresses. In response to energy deprivation, ribosomal biogenesis is repressed to preserve cellular function and maintenance. Other key regulators of ribosomal biogenesis such as the protein kinase Target of Rapamycin (TOR) are tightly regulated in response to stress.
Conclusions: Plants use translational control of gene expression to optimize growth and development in response to stress as well as to energy deprivation. This Botanical Briefing discusses the role of sucrose signalling in the translational control of bZIP11 and the regulation of ribosomal biogenesis in response to metabolic changes and stress conditions.
Key words: Sucrose signalling, Arabidopsis thaliana, bZIP11, translational control, ribosomal biogenesis, amino acid metabolism, TOR, SnRK1
Present address: Department of Biology, Faculty of Sciences, Urmia University, Urmia, Iran.
CiteULike 
Connotea 
Del.icio.us What's this?
Related articles in Ann Bot:
- ContentSnapshots
Ann Bot 2009 104: i.[Extract] [Full Text]
This article has been cited by other articles:
|
|
 |
|
  S. G. Kang, J. Price, P.-C. Lin, J. C. Hong, and J.-C. Jang The Arabidopsis bZIP1 Transcription Factor Is Involved in Sugar Signaling, Protein Networking, and DNA Binding Mol Plant, January 15, 2010; (2010) ssp115v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Yoshida, T. Suzaki, W. Tanaka, and H.-Y. Hirano The homeotic gene long sterile lemma (G1) specifies sterile lemma identity in the rice spikelet PNAS, November 24, 2009; 106(47): 20103 - 20108. [Abstract] [Full Text] [PDF]
|
|